极地研究

极地研究 ›› 2021, Vol. 33 ›› Issue (1): 128-138.DOI: 10. 13679/j.jdyj.20200046

• 研究进展 • 上一篇    下一篇

细菌抗冻蛋白研究进展及其应用潜力分析

高山惠1,2  廖丽2,3  胥义1  陈波2,3   

  1. 1上海理工大学, 医疗器械与食品学院, 上海 200093;
    2中国极地研究中心, 自然资源部极地科学重点实验室, 上海 200136;
    3    南方海洋科学与工程广东省实验室(珠海), 广东 珠海 519000
  • 收稿日期:2020-05-21 修回日期:2020-06-19 出版日期:2021-03-31 发布日期:2021-03-26
  • 通讯作者: 廖丽
  • 基金资助:
    国家重点研发计划(2018YFC1406702)资助

Review of bacterial antifreeze protein research and its potential applications

Gao Shanhui1,2, Liao Li2,3, Xu Yi 1, Chen Bo2,3   

  1. 1 School of Medical Devices and Food, Shanghai University of Technology, Shanghai 200093, China;
    2Polar Research Institute of China, Key Laboratory of Polar Science, Ministry of Natural Resources, Shanghai 200136, China;
    3Guangdong Provincial Laboratory of Southern Marine Science and Engineering (Zhuhai), Zhuhai 519000, China
  • Received:2020-05-21 Revised:2020-06-19 Online:2021-03-31 Published:2021-03-26

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摘要： 抗冻蛋白是一类在低温下抑制冰晶生长从而保护细胞免受冰晶伤害的特殊蛋白质。抗冻蛋白来源广泛, 包括鱼类、昆虫、植物、细菌、藻类和真菌等。相比动植物来源的抗冻蛋白, 目前针对细菌来源抗冻蛋白缺乏系统性综述与分析。因此重点描述了细菌来源抗冻蛋白的研究进展, 并以其中活性较高、研究较多的4个抗冻蛋白来源种属为代表, 详细介绍了细菌抗冻蛋白目前的研究现状、发展前景和应用潜力

关键词: 细菌, 抗冻蛋白, 极地, 研究进展, 应用

Abstract:

Antifreeze proteins (AFPs) are special proteins that inhibit the growth of ice crystals at low temperatures to protect cells from damage by ice crystals. They come from a wide range of sources, and have been found in fish, insects, plants, bacteria, algae and fungi. In contrast to research on AFPs derived from animals and plants, research on AFPs derived from bacteria has yet to be systematically reviewed and analyzed. Therefore, this review reports on the latest research findings on bacterial AFPs, focusing on four bacteria species and their AFPs. We also discuss the prospects and potential applications of bacterial AFPs.

Key words: bacteria, antifreeze protein, polar regions, research progress, application