EVALUATION OF THE EFFECT OF FLUORINE TOXICITY IN ANTARCTIC KRILL ON SOFT TISSUE IN RATS

doi:10.3724/SP.J.1084.2013.00078

Abstract

Abstract: The toxicity of fluorine (F) in Antarctic krill via animal experiment was evaluated. There were three groups in this experiment: the control group, the krill treatment group (150 mg?kg-1 F), the NaF treatment group (150 mg?kg-1 F). After three months, the rats were dissected and the liver, kidney, spleen, brain and testis samples were collected. Morphological change of these sample cells was assessed by H-E staining. There was no significant difference of weight and viscera coefficient among three groups. Except for testis, the other four soft tissues samples in the krill treatment group display some pathological changes, although the pathological changes in krill treatment group were fewer than that in NaF treatment group. These results revealed that the toxicity of equal quality F in Antarctic krill was lower than that in NaF, but it was still toxic for rats to consume the krill excessively. This study provides the direct scientific evidences for exploring further human consumption of krill.

Key words: Antarctic krill, fluorine, animal experiment, HE staining, pathological changes

Zhang Ling, Lu Xiaoqi, Wang Zhangmin, Qin Liqiang, Yuan Linxi, Yin Xuebin. EVALUATION OF THE EFFECT OF FLUORINE TOXICITY IN ANTARCTIC KRILL ON SOFT TISSUE IN RATS[J]. ADVANCES IN POLAR SCIENCE, 2013, 25(1): 78-83.

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