Based on the analysis of heavy metal contents in the core ANT30/P1-02, collected in Prydz Bay, East Antarctica during the 30th Chinese National Antarctic Research Expedition, variations in their enrichment characteristics and sources since the last interglacial period are discussed. The results show that the change trend of heavy metal enrichment coefficient was consistent with that of the heavy metal content. Several clear differences in the heavy metal content trend were observed, and can be used to characterize the glacial cycle. Notable enrichments were measured for Pb, Zn and particularly for Ba. Conversely, Ge, Cd and Fe elements were not enriched, or not noticeable, with relatively little difference in enrichment coefficient is not obvious in the glacial period. Moreover, Ca enrichment was observed in the last interglacial period. By estimating heavy metal inputs from different sources, five sources with large differences were identified. During the last glacial period, sources of Fe and Ge exhibited notable variations. Marked source variations were also measured for Ba, Ca, and Zn, but during the last interglacial period. Fe and Ca were more affected by inputs from rocks, whereas Ge, Ba and Zn were more affected by biogenic material inputs. The large source variations observed for Fe, Ge, Ba, Zn and Ca were consistent with the measured enrichment coefficient variations.