极地研究

极地研究 ›› 2020, Vol. 32 ›› Issue (2): 133-139.DOI: 10.13679/j.jdyj.20190034

• 研究综述 •    下一篇

极地微生物基因组挖掘现状与展望

廖丽,陈波   

  1. 中国极地研究中心, 上海 200136
  • 收稿日期:2019-07-08 修回日期:2019-07-31 出版日期:2020-06-30 发布日期:2020-06-30
  • 通讯作者: 廖丽
  • 基金资助:
    中国工程院战略研究项目(2018-ZD-08)资助

Current status and perspectives on genome mining of polar microorganisms

Liao Li, Chen Bo   

  1. Polar Research Institute of China, Shanghai 200136, China
  • Received:2019-07-08 Revised:2019-07-31 Online:2020-06-30 Published:2020-06-30

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摘要： 测序技术的快速发展极大地促进了微生物基因组相关研究。极地微生物基因组的测序与研究虽然启动略晚, 但迅速成为极地微生物研究的一个重要内容。极地微生物基因资源具有重要的战略意义与社会效益, 但针对极地微生物基因组的深入研究以及基因资源的深度挖掘仍然非常有限, 没有真正发挥基因组测序的作用与价值。本文总结了国际上极地微生物基因组相关研究现状与主要的研究方向, 分析了极地微生物基因组挖掘潜力与目前研究的不足之处, 并在此基础上提出了重点需要突破的方向。极地微生物基因资源潜力巨大, 加强对极地微生物基因资源的挖掘将为未来生物技术的发展提供更多可能性。

关键词: 极地微生物, 基因组, 基因资源, 基因组挖掘

Abstract: The rapid development of sequencing technology has greatly advanced research on microbial genomics. Although the initiation of polar microorganism genome sequencing was relatively late, it has become an important research area in the field of polar microbiology. The genetic resources of polar microorganisms hold strategic significance and social benefits. However, in-depth investigations of polar microbial genomes and genetic resources are quite limited, and the real power of genome sequencing has not been fully utilized. In this review, we summarize the current progress and research directions of polar microbial genomics, and analyze the shortcomings of current research and potential of genome mining. Accordingly, we propose key research directions requiring particular attention and breakthroughs. Overall, enhancing the mining of genetic resources from polar microorganisms provides more possibilities for future biotechnology.

Key words: polar microorganisms, genome, genetic resources, genomic mining