极地研究 ›› 1998, Vol. 10 ›› Issue (4): 68-72.

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南极环境对考察队员儿茶酚胺含量的影响

朱广瑾;段岩平;周朝凤;张莹;薛全福   

  • 出版日期:1998-12-30 发布日期:1998-12-30

CHANGES OF URINE AND PLASMA CATECHOLAMINE OF EXPEDITION MEMBERS IN ANTARCTIC ENVIRONMENT

  • Online:1998-12-30 Published:1998-12-30

摘要:

报道了中国第八次南极考察队(长城站)队员赴南极前、居留南极及回国后尿、血浆的去甲肾上腺素(NE)和肾上腺素(E)含量变化,以探讨考察队员在居留南极期间普遍存在生理和心理变化的物质基础。结果表明:考察队员到达长城站2周时尿中NE急剧增高(与赴南极前相比P<0.05),越冬后(居留南极1年2周)NE大幅度下降(与到达2周时相比P<0.001),考察结束回国后NE恢复到赴南极前水平。尿中E含量在到达南极2周时同样显著升高,且增高幅度大于NE(与赴南极前比较P<0.001),越冬后E水平比到达2周时有所降低(P<0.05),回国后E水平没有恢复。提示,儿茶酚胺变化参与综合应激反应过程,E受心理影响大于生理因素。还发现部分考察队员惧怕抽血,故测定尿儿茶酚胺含量更切实可行。经酸化处理的尿样品在短期内温度(室温)对儿茶酚胺含量影响不大,因此,从南极实地取样返回国内检测及进行南极医学方面的研究完全可行。

关键词: 南极,考察队员,儿茶酚胺

Abstract:

The changes of urine and plasma catecholamines, norepinephrine(NE) and epinephrine(E), were investigated in 16 Antarctic expedition members(Great Wall Station) under extreme environmental condition by Spectrophotofluorescent and radioenzymatic assay. Samples were taken at different time:(1)before leaving to Antarctica;(2)2 weeks after arrival at Antarctica;(3)1 year and 2 weeks after arrival and (4) after returning back to China.Results showed that a rapid increase of urinary NE in Antarctica (2) decreased significantly at(3),and returned to normal content at(4).The increase of urinary E was greater than that of NE at Antarctica (2),but kept high level at (4). The results indicated that activation of sympathetic system was involved in syndromic stress, especially psychological responses was associated with high E level. In addition, catecholamines were not affected by temperature and determinative time in room temperature during 3 monthes.