Abstract: Using visible/UV differential absorption spectroscopy,atmospheric ozone and NO 2 contents at Zhongshan Station during Antarctic ozone hole in 1991 are observed.The results show that the ozone depletion occurs rapidly during the middle of August and reaches a minimum value on October 3,and after 4 days the ozone content quickly returns to normal value. The variations of atmospheric ozone and NO 2 contents have a good positive correlation and the correlation coefficient reaches 0.69. During the ozone hole, the content of NO 2 is always on low level and the altitude of its layer is higher. It shows that the ozone depletion is not due to the catalytic loss process of odd nitrogen at Zhongshan Station during Antarctic Spring,1991.