极地研究

极地研究 ›› 1997, Vol. 8 ›› Issue (1-English): 72-76.

• 目次 • 上一篇    

Studies on the plasma tryptophan and urinary 5-hydroxy-3-indoleacetic acid in expedition members residing in Antarctica

 Xu Shuhuai1, Xue Quanfu1, Xue Zuohong2 and Wang Zonghui3   

  1. 1Institute of Basic Medical Sciences, CAMS; School of Basic Medicine, PUMC, Beijng 100005, China 2Department of Psychology, Peking Universtity, Beijing 100871, China 3Beijing Institute of Labor Hygiene and Occupational Diseases, Beijing 100020, China
  • 出版日期:1947-03-30 发布日期:1947-03-30
  • 通讯作者: Xu Shuhai
  • 基金资助:

    This project was supported by National Natural Science Foundation and the National Committee of Science and Technology.

Studies on the plasma tryptophan and urinary 5-hydroxy-3-indoleacetic acid in expedition members residing in Antarctica

 Xu Shuhuai1, Xue Quanfu1, Xue Zuohong2 and Wang Zonghui3   

  1. 1Institute of Basic Medical Sciences, CAMS; School of Basic Medicine, PUMC, Beijng 100005, China 2Department of Psychology, Peking Universtity, Beijing 100871, China 3Beijing Institute of Labor Hygiene and Occupational Diseases, Beijing 100020, China
  • Online:1947-03-30 Published:1947-03-30
  • Contact: Xu Shuhai
  • Supported by:

    This project was supported by National Natural Science Foundation and the National Committee of Science and Technology.

PDF (PC)

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摘要：

In order to clarify the possible relationship between the changes of behavior/personality and metabolic changes of 5-hydroxytryptamine (5-HT) in Antarctic expedition members, plasma tryptophan (Trp) and urinary 5-hydroxy-3-indoleacetic acid (5-HIAA) were studied for 24 winter-over and 19 summer-over members of the 8th and 11th CHINARE respectively. Results showed that plasma Trp decreased significantly after residing 1~3 months at Great Wall Station and did not recover on returning back to Beijing from Antarctica by two weeks travelling. Urinary 5-HIAA increased significantly after residing 6 months at Great Wall Station, and recovered on returning back to Beijing from Antarctica in the winter over members. The decrease of plasma Trp may be related to the decline of brain 5-HT which might play a role in the changes of behavior/personality . Increase of urinary 5-HIAA might reflect metabolic changes of 5-HT as a whole, but cold weather involving in the release response of platelet should be considered. Therefore, supplement of related food rich in Trp or intervention of L-Trp might be valuable.

关键词: Antarctica, expedition member, tryptophan, 5-hydroxy-3-indoleacetic acid

Abstract:

In order to clarify the possible relationship between the changes of behavior/personality and metabolic changes of 5-hydroxytryptamine (5-HT) in Antarctic expedition members, plasma tryptophan (Trp) and urinary 5-hydroxy-3-indoleacetic acid (5-HIAA) were studied for 24 winter-over and 19 summer-over members of the 8th and 11th CHINARE respectively. Results showed that plasma Trp decreased significantly after residing 1~3 months at Great Wall Station and did not recover on returning back to Beijing from Antarctica by two weeks travelling. Urinary 5-HIAA increased significantly after residing 6 months at Great Wall Station, and recovered on returning back to Beijing from Antarctica in the winter over members. The decrease of plasma Trp may be related to the decline of brain 5-HT which might play a role in the changes of behavior/personality . Increase of urinary 5-HIAA might reflect metabolic changes of 5-HT as a whole, but cold weather involving in the release response of platelet should be considered. Therefore, supplement of related food rich in Trp or intervention of L-Trp might be valuable.

Key words: Antarctica, expedition member, tryptophan, 5-hydroxy-3-indoleacetic acid