极地研究

极地研究 ›› 2023, Vol. 35 ›› Issue (3): 490-497.DOI: 10.13679/j.jdyj.20220424

• 研究进展 • 上一篇    

抗冻蛋白多维活性表征鉴定新进展

单妍妍1,2  廖丽2  胥义1  陈波2   

  1. 1上海理工大学, 健康科学与工程学院, 上海 200093;
    2中国极地研究中心(中国极地研究所), 自然资源部极地科学重点实验室, 上海 200136
  • 出版日期:2023-09-30 发布日期:2023-09-26
  • 通讯作者: 廖丽,胥义
  • 作者简介:单妍妍, 女, 1998年。硕士研究生, 主要从事极地微生物、新型低温保护剂研究。E-mail: 1448536559@qq.com
  • 基金资助:

    国家重点研发计划(2018YFC1406702)资助

Recent progress in the characterization of multidimensional activities of antifreeze proteins

Shan Yanyan1,2, Liao Li2, Xu Yi1, Chen Bo2   

  1. 1School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China;
    2Key Laboratory of Polar Science, MNR, Polar Research Institute of China, Shanghai 200136, China
  • Online:2023-09-30 Published:2023-09-26

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摘要：

抗冻蛋白(antifreeze protein)是一类能够控制冰晶、帮助生物免受低温损害的蛋白, 具有多种优良的抗冻活性。本文全面讨论了抗冻蛋白多种抗冻活性(冰面结合活性、热滞活性、重结晶抑制活性、冰晶修饰活性和冰粘附活性), 介绍了抗冻活性鉴定方法及其最新的进展。在此基础上, 总结了抗冻蛋白研究存在的问题与挑战, 并对其研究前景进行了展望。

关键词:

抗冻蛋白, 冰面结合, 热滞活性, 重结晶抑制, 冰晶修饰

Abstract:

Antifreeze proteins (AFPs) are proteins with a variety of activities that inhibit ice crystal growth and protect organisms from low-temperature damage. In this review, we described several activities of AFPs including ice adsorption, thermal retardation, recrystallization inhibition, ice crystal morphology modification and ice adhesion activities. Furthermore, we summarized specific methodologies and current advances in AFP characterization. Finally, we discussed remaining issues, challenges, and future directions in AFP research.

Key words:

antifreeze protein, ice adsorption, thermal retardation, recrystallization inhibition, ice crystal morphology modification